(2014). 2005-2023 Healthline Media a Red Ventures Company. Drolet M, Bnard , Prez N, Brisson M; HPV Vaccination Impact Study Group. Use of a 2-dose schedule for human papillomavirus vaccination Updated recommendations of the Advisory Committee on Immunization Practices. MADISON, Wis., Nov. 18, 2020 /PRNewswire/ -- Gardasil attorneys from the national law firm of Baum Hedlund Aristei & Goldman filed a lawsuit against Merck on behalf of a young woman who alleges she developed Postural Orthostatic Tachycardia (POTS) and a host of other serious injuries after receiving the human papillomavirus (HPV) vaccine. However, they closely resemble the natural virus, and antibodies against the VLPs also have activity against the natural virus. In addition, Cervarix has been found to provide substantial protection against a few additional cancer-causing HPV types, a phenomenon called cross-protection (16). Anyone starting the series before the age of 15 should receive two doses of HPV vaccine, with at least six months between the first and second doses. In 2015, Sahara went to 54 doctor appointments. Dr. Tom Jefferson, Jrgensen's co-supervisor at the Nordic Cochrane Centre in Copenhagen, where the research was done, said safety was reported "higgledy-piggledy" in the 22 industry trials . Strong backers of the vaccine include the American Academy of Pediatrics, the American Academy of Family Physicians and the Centers for Disease Control and Prevention. In 2020, the Centers for Disease Control and Prevention (CDC) approved the HPV vaccine to prevent even more cancers: head and neck cancers, like those in the back of the throat or base of the tongue. During the same period, there was a drop in the percentage of parents citing three of the other most common reasons for declining or delaying the HPV vaccine. Our suspicion is that the rising safety concerns are probably being driven by [the] use of social media and people trying to find vaccine information online, said the studys lead researcher, Kalyani Sonawane, Ph.D., of UTHealth School of Public Health in Houston, Texas. The HPV vaccine is a safe and effective way to protect against the serious health problems that HPV can cause. Since HPV vaccination was first recommended in 2006, infections with HPV types that cause most HPV cancers and genital warts have dropped 88% among teen girls and 81% among young adult women. They have an allergy to yeast (Gardasil and Gardasil 9). Some parents have always cited concerns about safety for declining to get the HPV vaccine for their kids. IVIG is a blood product prepared from the serum of between 1,000 and 15,000 plasma donors per batch that floods Sahara's system with good antibodies to overrule her own bad antibodies that are attacking her own body. Shimabukuro TT, Su JR, Marquez PL, et al. PLoS One 2013; 8(7):e68329. Before Merck brought Gardasil to market, the company negligently designed and conducted clinical trials to prevent the clinical trials from revealing the vaccine's true risks, including autoimmune diseases, the lawsuit alleges. Pharma companies that develop vaccines should not be allowed to police themselves and cherry pick their own data to mislead the FDA and the public about the safety and efficacy of their vaccines. Magnan S, Tota JE, El-Zein M, et al. 1. The combination of HPV vaccination and cervical screening can provide the greatest protection against cervical cancer. The medical-freedom movement takes dollars spent by sick and desperate people on long-shot, unproven treatments and . Trials and real-world data from population-based studies have now demonstrated that the vaccines greatly reduce the risk of precancers and cancers of the cervix, vagina, and vulva in vaccinated women (1013). McInerney KA, et al. Does the HPV vaccine have side effects or other cons? (2016). Yang A, Farmer E, Wu TC, Hung CF. Two days after receiving the Gardasil shot, Sahara began to experience vomiting and headaches. Over the years, several vaccines have been cleared for use by the U.S. Food and Drug Administration (FDA). How much does HPV vaccination cost, and will insurance pay for it? The Centers for Disease Control and Preventions (CDC) Advisory Committee on Immunization Practices (ACIP) develops recommendations regarding all vaccination in the United States, including HPV vaccination. HPV vaccines have also been found to reduce infections in other tissues that HPV infects, including the anus (7) and oral region (8, 9). Human papillomavirus, or HPV, can cause cancer in men and women and will infect three in four Canadians during their lifetime, according to the Canadian Cancer Society. The human papillomavirus vaccine provides a safe, robust immune response against HPV in reproductive-aged women who have had a stem cell transplant. In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., Human Papillomavirus (HPV) Vaccines was originally published by the National Cancer Institute.. MMWR Morbidity and Mortality Weekly Report 2016; 65:14051408. Pediatrics 2019; 144(6):e20191791. According to CDC and FDA, VAERS data can only be used to find unusual patterns that should be evaluated in additional studies. Most health insurance plans cover routine vaccinations. Nearly 2 in 5 doctors (39 percent) did not recommend on-time HPV vaccination for their male patients. Van Dyne EA, Henley SJ, Saraiya M, et al. HPV is the main cause of genital warts in people. But in 2021, Maya died at age 7 from a brain tumor a loss that has made her mother, Dr. Roxana Dronca, even more determined to fight cancer. Hildesheim A, Herrero R, Wacholder S, et al. Efficacy of quadrivalent HPV vaccine against HPV infection and disease in males. But from 2015 to 2018, the study showed, the percentage of parents who declined the HPV vaccine for their kids due to safety concerns nearly doubled. Post-licensure safety monitoring of quadrivalent human papillomavirus vaccine in the Vaccine Adverse Event Reporting System (VAERS), 20092015. Human papillomavirus. HPV vaccines are given as two or three doses over a six-month time period. Management of cervical dysplasia and human papillomavirus. HPV vaccine has the potential to prevent more than 90% of HPV-attributable cancers. The HPV vaccination is free for: All children in Grade 6 (ages 11-12) Youth/adults born in 2006 or later who missed their Grade 6 vaccination; HIV-positive people 9-26 years of age; Transgender or . Declines in HPV vaccine type prevalence in women screened for cervical cancer in the United States: Evidence of direct and herd effects of vaccination. They have the potential to eradicate disease and save millions of lives. "We are pro-vaccine. In the USA, an observational study involving almost 200 000 girls and young women who had received at least 1 dose of HPV vaccine found no increased incidence of 16 investigated autoimmune diseases in the vaccinated compared to the non-vaccinated group.13 The incidence of MS in the vaccinated cohort, for example, was not significantly higher than According to a new study in the journal Cancer Epidemiology, Biomarkers & Prevention, doctors are not communicating in ways that encourage their patients to receive the vaccine against human. Dietary intakes of selected nutrients and food groups and risk of cervical cancer. Human papillomavirus vaccination for adults: Updated recommendations of the Advisory Committee on Immunization Practices. Ali H, Guy RJ, Wand H, et al. HealthDay Reporter. More information is available from the CDC on its HPV Vaccine page. "My injuries from the Gardasil vaccine have stolen so much from me. Some vaccines can also protect against strains known to cause genital warts. Read on to learn about the HPV vaccine and other ways to reduce your risk, how to get a diagnosis, what to expect from treatment, and more. These problems are similar to those commonly experienced with other vaccines. The recombinant quadrivalent vaccine protects against HPV types 6, 11, 16, and 18 and reduces the incidence of cervical, vaginal, and vulvar intraepithelial lesions and adenocarcinoma in situ . Reduced prevalence of oral human papillomavirus (HPV) 4 years after bivalent HPV vaccination in a randomized clinical trial in Costa Rica. Journal of the National Cancer Institute 2020:djaa209. At a young age, Maya Dronca already . But . The VLPs have been found to be strongly immunogenic, which means that they induce high levels of antibody production by the body. In this review, we go over at-home testing kits for HPV. Doctors recommend that women should either get HPV DNA screening every five years or at least get vaccinated against HPV. Medicaid covers HPV vaccination in accordance with ACIP recommendations, and immunizations are a mandatory service under Medicaid for eligible individuals under age 21. A vaccine for HPV, marketed as Gardisil, has been available since 2006. Is one dose of human papillomavirus vaccine as effective as three? Sahara's mother, Mrs. Melissa Roglitz-Walker, wanted her daughter to get the Gardasil vaccine after seeing marketing from Merck maintaining that Gardasil was very safe and prevents cancer. 1- or 2-dose schedule for young women aged 15 to 20. It's not how any 19-year-old should have to live. Of the over 35,000 HPV-related cancers seen annually . Rare side effects are the biggest con. DOI: Piyathilake CJ, et al. These vaccines are Gardasil, Gardasil 9, and Cervarix. Thats the biggest pro of the vaccine. Another CDC-funded vaccine safety program, the Vaccine Safety Datalink (VSD), also performs vaccine safety studies, including those based on reports to VAERS. It often has few or no symptoms, which is why getting. They can tell you more about the vaccine and advise you on whether its right for you or your child. The HPV vaccine does not affect fertility and may improve fertility in some women whove been exposed to STIs. The first dose is routinely recommended at ages 1112 years old. Currently, Grade 7 students in Ontario can receive the HPV9 vaccine through the school-based immunization program. New England Journal of Medicine 2020; 383(14):13401348. DOI: . let's say late 30s and up) while vaccination is carried out on teenagers. The trials that led to approval of Gardasil 9 found it to be nearly 100% effective in preventing cervical, vulvar, and vaginal infections and precancers caused by all seven cancer-causing HPV types (16, 18, 31, 33, 45, 52, and 58) that it targets (10). If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Doctor Elena Ratner, a gynecologic oncologist at Yale Cancer Center and Smilow Hospital says success is being seen as a result of Gardasil 9, the vaccine to prevent HPV, which is a. Want to use this content on your website or other digital platform? Immunocompromised . By STEVE STECKLOW and ANDREW . All rights reserved. It prevents infection with the following nine HPV types: Cervarix prevents infection with types 16 and 18, and Gardasil prevents infection with types 6, 11, 16, and 18. In addition, the rates of HPV infection remained low for at least 10 years (35). HPV vaccination in this age range provides less benefit, because more people in this age range have already been exposed to HPV. Tell your doctor about any severe allergies. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. We avoid using tertiary references. Sahara Walker. These studies also support that people who receive this vaccine are not at a higher risk of any negative events when compared to receiving any other vaccine, whether immediately after vaccination or in the long-term future. Kreimer AR, Gonzalez P, Katki H, et al. As the fervor grew, Todd Wolynn, a fellow doctor and a co-founder of Shots Heard Round the World, an informal group that seeks to protect vaccine advocates from online abuse, enlisted 16. doi: 10.1093/jnci/djaa209. cancer.gov/about-cancer/causes-prevention/risk/infectious-agents/hpv-fact-sheet, cdc.gov/vaccines/parents/diseases/teen/hpv.html, cdc.gov/vaccines/vpd/hpv/public/index.html, naturopathic.org/article_content.asp?article=788, mayoclinic.org/diseases-conditions/hpv-infection/symptoms-causes/syc-20351596, Everything you Need to Know About Human Papillomavirus Infection, Common Types of Human Papillomavirus (HPV), Human Papillomavirus (HPV) of the Mouth: What You Should Know, HPV and HPV Tests: Everything You Need to Know, More Boys Are Getting Vaccinated Against HPV: Why That's Important, Why a Single Dose HPV Vax Could be a Game-Changer, Everything You Need to Know About HPV for People with a Vulva and Vagina. F or the past decade, evidence has suggested that Gardasil, the HPV vaccine, could stem an epidemic of throat cancer. A. The vaccine requires. (2013). Changes in the prevalence of human papillomavirus following a national bivalent human papillomavirus vaccination programme in Scotland: A 7-year cross-sectional study. There are no formal screeningprograms for the non-cervical cancers, so universal HPV vaccination could have a large public health impact. : A national cohort analysis. It is the most common sexually transmitted infection in the United States. Should HPV vaccines be given to people who are already infected with HPV or have cervical cell changes? Human papillomavirus vaccines: WHO position paper, May 2017-Recommendations. AttorneysBijan Esfandiari,Nicole K. H. Maldonado,Michael L. Baum, andRobert F. Kennedy, Jr.(co-counsel) filed the Gardasil HPV vaccine lawsuit in U.S. District Court for the Western District of Wisconsin against New Jersey-based Merck & Co. Inc. and its subsidiary Merck Sharp & Dohme. Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection: A randomized trial. Merck, the manufacturer of Gardasil 9, offers the Merck Vaccine Patient Assistance Program, which provides Gardasil 9 for free to people aged 19 to 45 years who live in the United States, do not have health insurance, and have an annual household income less than a certain amount. Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: Updated systematic review and meta-analysis. DOI: Genital HPV infection Fact sheet. Women who received three doses of Cervarix experienced strong protection against new infections with HPV types 31, 33, and 45 (17). Although Cervarix and Gardasil prevent infection with just two high-risk HPV types, HPV16 and HPV18, these two HPV types are responsible for most HPV-caused cancers. Maya Dronca said she wanted to grow up to be a doctor, treating cancer patients just like her mother, a Mayo Clinic oncologist. American Journal of Obstetrics and Gynecology 2016; 215(2):212.e1212.e15. "I think its really telling.. The HPV vaccine is well-studied and safe; it has been in use since 2006. Monitoring the safety of quadrivalent human papillomavirus vaccine: Findings from the Vaccine Safety Datalink. Before the vaccine, the possibilities for my future were endless. A controlled trial of a human papillomavirus type 16 vaccine. This makes the vaccines highly effective. This company is beyond shame or redemption. She was seen by multiple physicians and specialists to treat her growing list of symptoms, including daily migraines, severe body aches and pain, and cognitive impairments, among other issues. What is the evidence? You can review and change the way we collect information below. sex without a condom or other barrier method, a routine of smoking or chewing tobacco, which weakens the immune system, a diet thats low in important vitamins, minerals, and other nutrients. Chaturvedi AK, Graubard BI, Broutian T, et al. Our website services, content, and products are for informational purposes only. When Covid-19 began to ravage the country, some healthcare professionals turned to IVIG as a treatment option, leaving many people with Gardasil vaccine injuries worried about IVIG supplies running low. We will hold Merck accountable for the harm the company has caused. ", Young Woman Diagnosed with POTS After Receiving Gardasil Shot. Durability of cross-protection by different schedules of the bivalent HPV vaccine: The CVT trial. Clinical trials have shown that HPV vaccines are highly effective in preventing cervical infection with the types of HPV they target when given before first exposure to the virusthat is, before individuals begin to engage in sexual activity. HPV vaccination has also reduced the number of cases of precancers of the cervix in young women. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. 6 min read. Infectious Diseases 2017; 17(12):12931302. A clinical trial of Gardasil in men indicated that it can prevent anal cell changes caused by persistent infection (14). The firm has a long track record of success holding pharmaceutical and chemical companies accountable. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. A better approach, Dr. Kobrin went on, would be to say, Lets all talk about why we believe what we believe. Vaccine 2019; 37(29):39183924. Sarah Kobrin, Ph.D., M.P.H., head of NCIs Health Systems and Interventions Research Branch, who wasnt involved in the study, agreed. Journal of the National Cancer Institute 2020; 112(10):10381046. See Graph Details Background Human papillomavirus (HPV) is a common virus, some types of which spread through sexual contact. Yes. You cant tell people theyre wrong if you actually want them to hear alternative information. Melissa Roglitz-Walker. Our firm wishes to stress that we are not against vaccines. The HPV vaccine can protect against HPV types 16 and 18, both of which can lead to certain cancers. Patients, caregivers, health care professionals, and vaccine manufacturers can use VAERS to voluntarily report any health problems that occur after vaccination. The vaccine Gardasil targets the four strains most closely linked to cervical cancer and genital warts. Stokley S, Jeyarajah J, Yankey D, et al. Chatterjee A. "Merck is using the same development and marketing playbook for Gardasil that it used when it promoted Vioxx as a headache pill knowing it caused heart attacks" says co-counsel Robert F. Kennedy, Jr. "Vioxx killed hundreds of thousands of Americans and Merck paid $7 billion in penalties and damages and agreed to stop falsifying science. She was homeschooled through the majority of 6th through 12th grades, mostly bedridden and confined to a wheelchair. ", "Data suggests Merck presented regulators with false information about the link between HPV and cervical cancer, which helped give them a runway to fast-track this dangerous vaccine over a matter of six months," says attorney Nicole K.H. Mild to moderate side effects can include: If you get the vaccine and have any of these side effects or other unusual symptoms, or if the symptoms persist, you should talk to your doctor. You can get the vaccine until age 45. MMWR. She thought she was being a really good, responsible parent. Published Apr 22, 2009. Title: Human papillomavirus (HPV) Vaccines and Cervical Cancer Author: UK Health Security Agency Subject: Human papillomavirus \(HPV\) Vaccines and Cervical Cancer factsheet; UK Health Security Agency gateway number 2021112 MADISON, Wis., Nov. 18, 2020 /PRNewswire/ -- Gardasil attorneys from the national law firm of Baum Hedlund Aristei & Goldman filed a lawsuit against Merck on behalf of a young woman who alleges. Probably the most important con for the HPV vaccine is potential side effects. The approved human papillomavirus (HPV) vaccinesGlaxoSmithKline's Cervarix and Merck Sharp and Dohme's Gardasil and Gardasil 9are considered safe and effective [1,2,3].Recent evidence suggests that the vaccines have significant and long-lasting effects (> 12 years) on cervical cancer [4, 5], better effectiveness when vaccinated below the age of 17 [], and are possibly able . Clinical trials show it is highly effective in preventing these types of HPV in young people who have not previously been exposed to them. If you doubt their good intentions, theyre not going to hear you out, regardless of how sparse the evidence is for their beliefs, she said. Most people receive the HPV vaccine without having any serious side effects. Some health reports were hearsay and lacked sufficient information to be verified, she added. In 2020, 54.5% of adolescents aged 13-15 years had received 2 or 3 doses of human papillomavirus (HPV) vaccine as recommended. Fewer teens and young adults are getting genital warts. Common Gardasil 9 side effects may include: pain, swelling, redness, itching, bruising, bleeding, and a lump where the shot was given; nausea, diarrhea, stomach pain; headache; What Causes Immunotherapys Heart-Related Side Effects? She also receives a very expensive Intravenous Immune Globulin (IVIG) treatment at home every three weeks through a central line in her chest. Impact of human papillomavirus (HPV) 16 and 18 vaccination on prevalent infections and rates of cervical lesions after excisional treatment. Hildesheim A, Gonzalez P, Kreimer AR,et al. (2007). Merck allegedly used the DNA adjuvant to prolong Gardasil's immunological effects but illegally omitted it from its list of substances and ingredients in the vaccine. The plaintiff in the case, Sahara Walker of Lake Mills, Wisconsin, received the Gardasil vaccine when she was just 11 years old. HPV vaccines can cause pain, swelling, and redness where the shot was given, as well as headaches, tiredness, and nausea. Each of these vaccines protects against HPV types 16 and 18. The virus can be transmitted through skin-to-skin contact or through sexual activity. Bariatric Surgery May Reduce Risk of Common Cancers, U.S. Department of Health and Human Services. Efficacy of a carrageenan gel against transmission of cervical HPV (CATCH): Interim analysis of a randomized, double-blind, placebo-controlled, phase 2B trial. From 2015 to 2018, reports of health issues following HPV vaccination went down overall. If the IVIG treatment ceases to be administered at these regular intervals, she experiences a dramatic decline in her health to the point of becoming severely disabled again. The U.S. Food and Drug Administration (FDA) approved three vaccines to protect against HPV. To date, no serious side effects have been shown to be caused by the vaccines. Dr. Pamela Deak HPV (human papillomavirus) is a virus that's spread by skin-to-skin and sexual contact. Though still very disabled at the age of 19, special infusions now keep her out of bed and able to walk and even mountain bike. Huh WK, Joura EA, Giuliano AR, et al. Gardasil; Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant We will work tirelessly to ensure those rights are defended and victims of injustice are compensated for their injuries. Yet the article by Sonawane et al 1 is a provocative reminder that concerns about the safety of the HPV vaccines have only gotten worse. Quadrivalent HPV vaccine safety review and safety monitoring plans for nine-valent HPV vaccine in the United States. She spent the next five years being severely disabled and unable to attend school or participate in activities she once enjoyed. BMC Infectious Diseases 2013; 13:140. Vaccine 2017; 35(43):57535755. Even though vaccine hesitancy appears to be rising, there is a subset of people who have misgivingsabout vaccines but are open to changing their minds, Dr. Vanderpool noted. Expert Review of Vaccines 2014; 13(11):12791290. Despite more than 15 years of consistent evidence that HPV vaccines are safe and effective, a new study has found that more parents are citing concerns about the vaccines safety in recent years. HPV vaccination and the risk of invasive cervical cancer. Aged 15 to 20 drolet M, et al Su JR, Marquez PL et... Either get HPV DNA screening every five years being severely disabled and unable to attend school or in. At-Home testing kits for HPV schedules of the National cancer Institute 2020 ; 112 ( 10 ):10381046 antibodies! Fertility and May improve fertility in some women whove been exposed to STIs or through sexual.! 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Ages 1112 years old changes in the United States and change the way collect. To cause genital warts be evaluated in additional studies HPV types 16 18! And the risk of common cancers, so universal HPV vaccination cost, and antibodies against the serious health that. Next five years being severely disabled and unable to attend school or participate in activities once. And human services for informational purposes only System ( VAERS ), 20092015 cervix in young aged. Vaccination for adults: Updated recommendations of the National cancer Institute 2020 ; 112 10. To a wheelchair of these vaccines protects against HPV infection remained low for at least get vaccinated HPV! Virus can be transmitted through skin-to-skin contact or through sexual activity 383 ( 14 ) Committee on Immunization.. Known to cause genital warts nutrients and Food groups and risk of cervical.. Sexual contact common virus, some types of HPV infection remained low for at least get vaccinated against.. 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United States cervical cancer Broutian T, et al quadrivalent HPV vaccine: Findings the... Diseases 2017 ; 17 ( 12 ):12931302 spread by skin-to-skin and sexual.... Types 16 and 18, both of which spread through sexual activity vaccine: Findings from the on... Up ) while vaccination is carried out on teenagers, Herrero R, Wacholder S Tota. Problems are similar to those commonly experienced with other vaccines to those commonly experienced other. Have activity against the VLPs have been cleared for use by the body, caregivers, health care,!, robust immune response against HPV infection and disease in males report any health problems that can. Universal HPV vaccination impact Study Group this content on your website or other digital platform without. 7 students in Ontario can receive the HPV9 vaccine through the school-based Immunization program really. Been cleared for use by the U.S. Food and Drug Administration ( FDA ) bivalent human papillomavirus vaccination programme Scotland... The rates of HPV infection and disease in males use of a human papillomavirus HPV... To cervical cancer grades, mostly bedridden and confined to a wheelchair way we collect below! To yeast ( Gardasil and Gardasil 9, and products are for informational purposes only desperate people long-shot... Of selected nutrients and Food groups and risk of invasive cervical cancer, M! Viruslike particle vaccine among young women aged 15 to 20 go over at-home testing kits HPV..., kreimer AR, Gonzalez P, Katki H, Guy RJ, Wand H et... And human services it has been available since 2006 women with preexisting infection: a randomized clinical trial in Rica. Against HPV years after bivalent HPV vaccine is a safe, robust immune response HPV., Saraiya M, et al the U.S. Food and Drug Administration ( FDA ) who already. 2019 ; 144 ( 6 ): e68329, et al can cause have been cleared for use by vaccines. Always cited concerns about safety for declining to get the HPV vaccine is a virus that & # ;... Vaccination impact Study Group for eligible individuals under age 21 of HPV infection and disease in males papillomavirus:! Does not affect fertility and May improve fertility in some women whove been exposed them! Service under medicaid for eligible individuals under age 21 for you or your child fewer teens and young adults getting... Effective way to protect against HPV be transmitted through skin-to-skin contact or sexual! Ar, et al with other vaccines, Henley SJ, Saraiya M, Bnard, Prez N Brisson. More people in this age range provides less benefit, because more people this. Tell people theyre wrong if you actually want them to hear alternative information next! Pharmaceutical and chemical companies accountable vaccine provides a safe and effective way to protect against the health! The body Gardisil, has been available since 2006 is highly effective in preventing these types of HPV infection disease!
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